Mutagenic probability estimation of chemical compounds by a novel molecular electrophilicity vector and support vector machine
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چکیده
منابع مشابه
Mutagenic probability estimation of chemical compounds by a novel molecular electrophilicity vector and support vector machine
MOTIVATION Mutagenicity is among the toxicological end points that pose the highest concern. The accelerated pace of drug discovery has heightened the need for efficient prediction methods. Currently, most available tools fall short of the desired degree of accuracy, and can only provide a binary classification. It is of significance to develop a discriminative and informative model for the mut...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2006
ISSN: 1367-4803,1460-2059
DOI: 10.1093/bioinformatics/btl352